Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars

Patterning is a critical step during organogenesis and is closely associated with the physiological function of organs.Tooth root shapes are finely tuned to provide precise occlusal support to facilitate the function Transfer Papers of each tooth type.However, the mechanism regulating tooth root patterning and development is largely unknown.In this

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Magnetic Resonance Imaging during Proton Therapy Irradiation Allows for the Early Response Assessment of Pediatric Chordoma

Chordoma in pediatric patients is very rare.Proton therapy has become a gold standard in the treatment of these neoplasms, as high dose escalation can be achieved regarding the target while maximizing the sparing of the healthy tissues near the tumor.The aim of the work was to assess the evolution of morphological sequences during treatment using T

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